2. Cell Cycle/DNA Damage
  3. Checkpoint Kinase (Chk)
  4. CHK-IN-1

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

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CHK-IN-1

CHK-IN-1 Chemische Struktur

CAS. Nr. : 1278405-51-8

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CHK-IN-1 Related Antibodies

Top Publications Citing Use of Products

Alle Checkpoint Kinase (Chk) Isoform-spezifische Produkte anzeigen:

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Chk1 Chk2 BUBR1

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Beschreibung

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

IC50 & Target[1]

Chk1

 

Chk2

 

In Vitro

CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CHK-IN-1 Related Antibodies
Molekulargewicht

407.89

Formel

C18H19ClFN5OS
CAS. Nr.
SMILES

O=C(C1=NN=C(N[C@@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
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CHK-IN-1 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CHK-IN-11278405-51-8Checkpoint Kinase (Chk)Inhibitorinhibitorinhibit

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